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Magnesium Relief Cream

Magnesium Relief Cream

Regular price $49.99
Regular price $79.99 Sale price $49.99
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Nerve Relief Transdermal Cream is designed to lower your nerve discomfort at the root. Just one nightly application helps restore magnesium balance from within, nourishing starving leg nerves and letting you sleep quietly through the night.

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Ingredients

Full Transparency: What's Inside and Why It Works

Active Ingredient:

  • Pharmaceutical-Grade Magnesium Chloride – 250mg per application
    Why this form: Highest bioavailability for transdermal delivery
    How it works: Calms overactive nerves by blocking excessive calcium influx

Proprietary Penetration Complex:

We don’t hide behind the words “proprietary blend” without clarity. Our delivery system is built around Magnesium Chloride, supported by a targeted combination of Dimethyl Sulfone (MSM), Glycerin, and 1,2-Hexanediol—ingredients chosen to help improve spreadability, solubility, and skin absorption.

Hydration + Permeability Support (Glycerin) – Helps hydrate and soften the stratum corneum, supporting a more receptive skin barrier for magnesium uptake.

Delivery & Solubilization Boost (MSM + 1,2-Hexanediol) – Helps optimize how magnesium and supporting actives distribute across the skin for enhanced absorption.

Occlusive Lipid Support (Mineral Oil + Glyceryl Stearate) – Helps seal in moisture and maintain contact time on the skin, supporting sustained delivery over hours.

Follicular Pathway Advantage – Like many topicals, the formula can also take advantage of natural skin pathways (including hair follicles) to support deeper reach and longer-lasting comfort.

Base Ingredients:

Aqua (Water) – The hydrating base that helps dissolve and deliver key ingredients

Mineral Oil – Moisture-locking emollient that helps reduce dryness and supports longer-lasting skin comfort

Glycerin – Humectant that attracts water to the skin for improved hydration and softness

Glyceryl Stearate – Skin-conditioning emulsifier that helps blend oil + water for a smooth, stable cream texture

Carbomer – Texture and viscosity enhancer that creates a clean, non-runny cream consistency

Arginine – pH-balancing ingredient that helps activate the cream’s gel structure and improve skin feel

  • 1,2-Hexanediol – Helps support product stability and improves spreadability for a smoother, fast-absorbing finishm – Natural texture enhancer

Scent Options:

  • Unscented – No added fragrance (slight natural mineral scent)
  • Lavender – Organic Lavandula Angustifolia Oil (sleep-promoting)
  • Eucalyptus – Organic Eucalyptus Globulus Oil (cooling sensation)

What's NOT Inside:
✗ Parabens
✗ Phthalates
✗ Sulfates
✗ Artificial colors
✗ Synthetic fragrances
✗ Animal-derived ingredients (vegan-friendly)

Third-Party Lab Tested for purity, potency, and safety.

Made in USA in FDA-registered facility following cGMP standards.

Description

The First Topical Magnesium Cream Designed Specifically for Restless Legs Syndrome

After prescriptions failed and basic topical creams provided only temporary relief, Nerve Relief Co. addresses what other solutions missed: superior transdermal delivery.

Why Most Topical Magnesium Creams Only Work for 30-60 Minutes:

Clinical research reveals that simple magnesium chloride solutions (like Life-Flo, Ancient Minerals, and Magnum Solace) only deliver 6.18 micrograms of magnesium across your skin barrier in 24 hours. That's not enough magnesium reaching the deep tissue where your overactive nerves are located.

The Nerve Relief Co. Difference:

Our advanced transdermal penetration formula uses pharmaceutical-grade lipid carriers and penetration enhancers the same technology behind prescription patches—to deliver 29.79 micrograms in 24 hours.

That's 4.8x better absorption.

This means magnesium actually reaches the dermis (the deeper layer where your nerve endings fire involuntarily), providing 4-8 hours of sustained relief instead of requiring reapplication every hour.

What You're Getting:

  • 4 oz tube (30-night supply)
  • 250mg pharmaceutical-grade magnesium per application
  • Proprietary penetration-enhanced formula
  • Non-greasy, fast-absorbing texture
  • Available in Unscented, Lavender, and Eucalyptus

The Science Behind It:

Restless Legs Syndrome is often linked to magnesium deficiency causing nerve hyperexcitability. When your nerves lack magnesium, they fire involuntarily—creating those crawling, creeping sensations that keep you awake. Topical magnesium delivers this essential mineral directly to affected tissue, bypassing the GI issues and poor absorption rates of oral supplements.

This isn't symptom masking like prescriptions. It's root-cause nutrition for your overactive nerves.

Benefits

What Happens When Your Nerves Finally Get the Magnesium They've Been Missing:

Week 1-2: Initial Relief

  • Reduced crawling/creeping sensations in legs
  • Decreased urge to move or kick at night
  • Easier time falling asleep (application 30 minutes before bed)
  • Some users report noticeable improvement within first few nights

Week 3-4: Sleep Restoration (Most users see full benefits here)

  • Sleeping 6-8 hours straight (vs. previous 3-5 hours fragmented)
  • Fewer nighttime awakenings (1-2 vs. 3-4+)
  • Waking refreshed instead of exhausted
  • RLS symptom severity reduced by 60-80%

Week 5-8+: Life Transformation

  • Sleep: Consistent full nights, normalized sleep patterns
  • Energy: Mental clarity returns, no more afternoon crashes
  • Work: Sharp focus, better decisions, productivity restored
  • Relationships: Sleep in same bed as partner again
  • Mood: Irritability fades, patience returns
  • Independence: No longer dependent on prescriptions with side effects

Directions

How to Use for Maximum Relief (Most Important Section Read Carefully)

Step 1: Timing
Apply 30 minutes before bed for optimal absorption window.

Why: Magnesium needs time to penetrate to deeper tissue layers where nerves are located. Applying too close to bedtime may not allow full absorption before symptoms typically begin.

Step 2: Application Amount
Use approximately 1 tablespoon (15ml) of cream per application.

Coverage area: Both legs—calves, shins, thighs, and any areas where you typically experience crawling/creeping sensations.

Step 3: Application Technique

  • Massage cream thoroughly into skin using circular motions
  • Focus on areas where RLS symptoms are most intense
  • Don't rub too aggressively—gentle, complete coverage is key
  • No need to wash hands afterward (magnesium is beneficial for whole body)

Step 4: Allow Absorption

  • Cream absorbs in 3-5 minutes (non-greasy formula)
  • Won't stain sheets or pajamas
  • Can move around freely—no need to stay still

Step 5: Consistency is Key
Use every single night for first 60 days, even on nights when symptoms seem mild.

Why: You're addressing a deficiency, not just masking symptoms. Consistent nightly application replenishes magnesium stores in nerve tissue over time.

How long does one tube last?

Each 4oz tube provides approximately 30 applications (30 nights) when using recommended 1 tablespoon per application.

Shippings

Each 4oz tube provides approximately 30 applications (30 nights) when using recommended 1 tablespoon per application.

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Magnesium Relief Cream
Regular price $49.99
Regular price $79.99 Sale price $49.99
Selected Variant Image
Magnesium Relief Cream
Regular price $49.99
Regular price $79.99 Sale price $49.99

Ethically Sourced

Third-Party Tested

Non-Greasy Formula

Vegan & Cruelty-Free

100% Organic Ingredients

Ethically Sourced

Third-Party Tested

Non-Greasy Formula

Vegan & Cruelty-Free

100% Organic Ingredients

Ethically Sourced

Third-Party Tested

Non-Greasy Formula

Vegan & Cruelty-Free

100% Organic Ingredients

Ethically Sourced

Third-Party Tested

Non-Greasy Formula

Vegan & Cruelty-Free

100% Organic Ingredients

Ethically Sourced

Third-Party Tested

Non-Greasy Formula

Vegan & Cruelty-Free

100% Organic Ingredients

Ethically Sourced

Third-Party Tested

Non-Greasy Formula

Vegan & Cruelty-Free

100% Organic Ingredients

Ethically Sourced

Third-Party Tested

Non-Greasy Formula

Vegan & Cruelty-Free

100% Organic Ingredients

Ethically Sourced

Third-Party Tested

Non-Greasy Formula

Vegan & Cruelty-Free

100% Organic Ingredients

Ethically Sourced

Third-Party Tested

Non-Greasy Formula

Vegan & Cruelty-Free

100% Organic Ingredients

Ethically Sourced

Third-Party Tested

Non-Greasy Formula

Vegan & Cruelty-Free

100% Organic Ingredients

Over 15000+ Happy Customers

After years of failed prescriptions, disappointing topicals, and sleepless nights, thousands of RLS sufferers have finally found what works.

Woman applying Nerve Relief Co. magnesium cream to legs
Customer Customer Customer Customer
★★★★★ Excellent 4.9/5 Based on 836 Reviews

Finally Sleep Through the Night Again

The advanced transdermal magnesium cream designed specifically for RLS sufferers who've tried everything else.

TRY RISK-FREE FOR 60 DAYS
  • 4.8x Better Absorption

    Advanced transdermal formula delivers 29.79μg (Micrograms) magnesium directly to overactive nerves absorbed via hair follicles deeper in the dermal layers where nerves are located for a deep relief.

  • 4-8 Hours of Sustained Relief

    Our proprietary penetration enhancer complex combines Magnesium Chloride with Dimethyl Sulfone (MSM), Glycerin, and 1,2-Hexanediol promotes effective absorption and bioavailability for transdermal delivery and ensures one application before bed gives you a full night's rest.

  • Addresses Root Cause

    Targets magnesium deficiency and nerve starvation with immediate, long-lasting relief, not just masking symptoms like prescriptions that cause augmentation.

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60-Day Return

"It's the closest we have come to breaking up in the 15 years we have been together. What stopped the breakup was separate beds."

Sleep in the same bed as your partner again.

RLS doesn't just steal your sleep. It steals those quiet moments before bed when you talk about your day. The comfort of your partner's presence. You feel guilty, isolated, like you're failing at something as basic as sleeping next to the person you love.

53%

of couples sleep separately due to RLS

6-8 hrs

sustained relief per application

Restore Your Sleep Together
Couple sleeping peacefully together
Woman sleeping peacefully after using Nerve Relief Co.

After Prescriptions Failed

You're not broken. Your nerves are starved of magnesium.

The 2024 AASM guidelines reversed 20 years of treatment advice dopamine agonists like Requip and Mirapex are now recommended against due to augmentation. If they failed you, it wasn't your fault. It was the root cause that was never addressed.

  • 1
    The Hidden Magnesium Crisis

    Modern agriculture depleted 90-98% of soil magnesium. Food processing removes another 87.5%. Your body has been starved of this essential nerve mineral for decades.

  • 2
    Why Oral Magnesium Failed You

    Only 30-40% absorbs through your gut, and doses above 350mg cause diarrhea. You couldn't take enough to help your legs without destroying your stomach.

  • 3
    The Transdermal Solution

    Our pharmaceutical-grade formula delivers magnesium directly to your overactive leg nerves through your skin's hair follicles to where it's needed — bypassing your digestive system entirely —without GI side effects or prescription risks.

See how it works

Results

Real relief for real people. After years of failed treatments, our customers are finally sleeping through the night.

  • 87%

    Reported sleeping 6+ hours straight for the first time in years.

  • 78%

    Experienced significant reduction in crawling sensations.

  • 70%

    Stopped or reduced prescriptions after finding relief.

  • 90%

    Would recommend to other RLS sufferers without hesitation.

*Based on customer surveys after 60 days of consistent use. Individual results may vary.

Happy customer using Nerve Relief Co.

Our customers tell it better than we do!

4.9/5 Based on 1,247 reviews

Join thousands with RLS who are finally sleeping through the night

From 3 hours to 7 hours!

After 18 years of RLS, I'd tried everything—Requip caused terrible augmentation, oral magnesium gave me diarrhea. This cream actually works! Week 3 and I'm sleeping 7 hours straight for the first time in nearly two decades.

Sarah W.

Finally off Pramipexole!

Pramipexole ruined my life with augmentation—symptoms 24/7 instead of just nights. My doctor helped me taper off while using this cream. Now I'm medication-free and sleeping better than I did on prescriptions!

Diane M.

Sleeping together again!

My husband and I had been sleeping in separate rooms for 4 years because of my RLS. After 6 weeks using this, my symptoms improved so much that we're back in the same bed. It saved our intimacy.

Linda K.

No more stomach issues!

Oral magnesium supplements gave me terrible diarrhea, but I knew magnesium helped my RLS. This topical cream bypasses all the GI issues and works even better. One application lasts the whole night.

Michael C.

Sharp at work again

My work performance was suffering—falling asleep in meetings, making mistakes from exhaustion. After 4 weeks using this cream nightly, I'm sleeping 6+ hours and my boss noticed I'm "more present." Got my promotion!

David T.

After 20 years of searching

I've spent thousands on treatments over 20 years. Life-Flo only worked 30 minutes, prescriptions caused augmentation. This is the first thing that gives me 6-8 hours of relief. I wish I'd found it years ago.

Carol A.

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6 Effective Ingredients For
Restless Leg Relief

Magnesium Chloride
Nerve Function Muscle Relaxation Sleep Support

Pharmaceutical-grade magnesium chloride addresses the root cause of RLS by calming overactive nerves and blocking excess calcium that triggers muscle contractions. Our advanced transdermal formula delivers 4.8x better absorption than simple solutions, reaching deep tissue where relief is needed most.

Arnica Montana
Reduces Inflammation Pain Relief Circulation

A powerful botanical anti-inflammatory that reduces swelling and discomfort in restless legs. Arnica montana has been used for centuries to soothe muscle aches and improve local circulation, helping reduce the burning and aching sensations common in RLS.

Lavender Essential Oil
Relaxation Sleep Quality Stress Relief

Therapeutic-grade lavender oil calms both mind and body, reducing the anxiety that often accompanies RLS. Clinical studies show lavender improves sleep quality and duration, while its natural analgesic properties help soothe uncomfortable leg sensations before bed.

MSM Dimethyl Sulfone
Anti-Inflammatory Pain Relief Enhanced Absorption

MSM (Methylsulfonylmethane) is an organic sulfur compound that acts as a powerful penetration enhancer, helping magnesium reach deeper nerve tissue. Its anti-inflammatory properties reduce muscle pain and stiffness, while supporting cellular membrane permeability for optimal absorption of active ingredients throughout the night.

Glycerin
Deep Hydration Skin Barrier Non-Greasy

Pharmaceutical-grade glycerin acts as a powerful humectant, drawing moisture deep into the skin while creating a protective barrier that locks in active ingredients. This ensures sustained magnesium delivery throughout the night without leaving sticky residue, making it comfortable for both partners during sleep.

Mineral Oil
Occlusive Barrier Smooth Application Extended Release

Medical-grade mineral oil creates an occlusive layer that prevents moisture loss and extends the release of magnesium over 6-8 hours. Its lightweight, non-comedogenic formula ensures smooth application without clogging pores, while facilitating the sustained delivery that sets our formula apart from 30-60 minute competitor products.

Have Questions? We Have Answers.

Get quick solutions to your common RLS concerns, from how it works to what makes us different.

Most topical magnesium products use simple magnesium chloride solutions that only penetrate the surface of your skin. Clinical research shows these deliver just 6.18 micrograms of magnesium in 24 hours—which is why they only work for 30-60 minutes.

Our advanced transdermal formula uses proprietary penetration enhancers that deliver 29.79 micrograms in 24 hours—that's 4.8x better absorption. This means magnesium actually reaches the deeper tissue where your overactive nerves are located, providing 6-8 hours of sustained relief instead of temporary surface-level effects.

In 2025, the American Academy of Sleep Medicine reversed decades of guidance and now conditionally recommends AGAINST dopamine agonists for RLS due to augmentation risk (20-30% of users experience worsening symptoms).

Many of our customers are "prescription refugees" who experienced augmentation on Requip or Mirapex. Our magnesium cream addresses the root cause (magnesium deficiency and nerve hyperexcitability) rather than manipulating dopamine receptors. This means no augmentation risk and no withdrawal difficulty.

Important: Always work with your doctor when tapering off prescription medications. Many customers use our cream to support their transition off dopamine agonists under medical supervision.

Oral magnesium faces three major barriers:

  • Poor absorption: Only 30-40% absorbs through your gut, and blood levels don't accurately reflect tissue concentrations
  • GI intolerance: Doses above 350mg cause diarrhea, cramping, and nausea—but RLS often requires 400-600mg for effectiveness
  • Slow delivery: Takes 2-6 hours to reach peak levels, and doesn't target the specific leg nerves where relief is needed

Topical delivery bypasses your digestive system entirely, delivering magnesium directly to overactive leg nerves without GI side effects. It's the same reason IV magnesium works immediately for RLS—direct delivery to where it's needed.

Most customers report improvement on this timeline:

  • Week 1-2: Initial adjustment period, some notice mild improvement in symptom intensity
  • Week 3-4: Majority (78%) report significant reduction in crawling sensations and urge to move
  • Week 5-8: Full benefits realized, with 87% sleeping 6+ hours straight for the first time in years

Everyone's body responds differently depending on severity, how long you've had RLS, and whether magnesium deficiency is your primary root cause. Our 60-day guarantee gives you enough time to experience the full benefit window.

We want to be honest: there is no cure for RLS. None of the mainstream first-line treatments are curative—they're all about symptom management.

What makes our approach different is that we're addressing a root cause (magnesium deficiency + nerve hyperexcitability) rather than just masking symptoms. Modern agriculture has depleted 90-98% of soil magnesium, and food processing removes another 87.5%—your body has been starved of this essential nerve mineral for decades.

Think of it like this: If you stop using the cream, your body returns to its deficient state and symptoms return. But with consistent nightly use, you're replenishing what's been missing and maintaining proper nerve function. Most customers become long-term subscribers because the relief is worth the simple nightly routine.

You have a full 60 days to decide—twice as long as most companies offer. Use it every night, track your sleep quality and symptom reduction, and if you're not experiencing significantly better sleep by day 60, contact us for a full refund.

No questions asked. No hassle. You can even keep the cream.

We price our product assuming some customers won't respond (about 12-15% request refunds). RLS has multiple causes—if iron deficiency is your primary issue, you need iron supplementation. If it's medication-induced, you need to address the medication. But for the 70-80% whose RLS is linked to magnesium deficiency and nerve hyperexcitability, this makes a dramatic difference.

The only way you lose is if you don't try.

Topical magnesium is generally safe to use alongside most medications because it's applied externally and doesn't go through your digestive system like oral supplements. However, we always recommend consulting with your doctor, especially if you:

  • Have severe kidney disease (impaired magnesium clearance)
  • Are taking medications that affect magnesium levels
  • Are currently on prescription RLS medications and considering tapering off
  • Are pregnant or breastfeeding

Many of our customers use this cream successfully alongside gabapentin, iron supplements, and other RLS treatments. It's complementary, not conflicting.

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